Updated for Data 2026-03-17Early Access — numbers may shift with patches.
Knockout Blow
Regent · Attack · Uncommon · 3 cost
Base
Upgraded
Card text
Deal 30 damage. If this kills an enemy, gain 5 Stars.
Knockout Blow+
Deal 38 damage. If this kills an enemy, gain 5 Stars.
Builds that use Knockout Blow
Archetypes that draft this card in real runs, with the role it plays.
Build context
See the Regent build hub for archetypes that feature this card in real runs.
Related cards
Knockout Blow FAQ
- Should I upgrade Knockout Blow in Slay the Spire 2?
- Compare the upgraded text: Deal 38 damage. If this kills an enemy, gain 5 Stars.. If the upgrade lowers cost, adds damage/block, or enables a combo piece, it is usually high priority.
- What builds use Knockout Blow?
- Knockout Blow appears in 2 tracked builds: The Aligned Crown (S-tier, flex pick), Constellation Engine (A-tier, flex pick).
- What character uses Knockout Blow?
- Knockout Blow is tagged as a Regent card. See the Regent build hub for archetypes that care about it.
Patch history
SpireForge snapshots card text from Untapped exports dated 2026-03-17. When Mega Crit ships a balance patch, we re-run the scraper and refresh every affected URL—see /patches for the editorial log.