Should I upgrade Devastate in Slay the Spire 2?

Compare the upgraded text: Deal 40 damage.. If the upgrade lowers cost, adds damage/block, or enables a combo piece, it is usually high priority.

What builds use Devastate?

Devastate appears in 1 tracked build: Iron Crown (B-tier, core card).

What character uses Devastate?

Devastate is tagged as a Regent card. See the Regent build hub for archetypes that care about it.

Updated for Data 2026-03-17Early Access — numbers may shift with patches.

Devastate

Regent · Attack · Uncommon · 1 cost

Base

Upgraded

Card text

Deal 30 damage.

Devastate+

Deal 40 damage.

Builds that use Devastate

Archetypes that draft this card in real runs, with the role it plays.

BIron CrownRegent · Core card

Build context

See the Regent build hub for archetypes that feature this card in real runs.

Related cards

Devastate FAQ

Should I upgrade Devastate in Slay the Spire 2?: Compare the upgraded text: Deal 40 damage.. If the upgrade lowers cost, adds damage/block, or enables a combo piece, it is usually high priority.
What builds use Devastate?: Devastate appears in 1 tracked build: Iron Crown (B-tier, core card).
What character uses Devastate?: Devastate is tagged as a Regent card. See the Regent build hub for archetypes that care about it.

Patch history

SpireForge snapshots card text from Untapped exports dated 2026-03-17. When Mega Crit ships a balance patch, we re-run the scraper and refresh every affected URL—see /patches for the editorial log.