Updated for Data 2026-03-17Early Access — numbers may shift with patches.

Sleight of Flesh

Necrobinder · Power · Uncommon · 2 cost

Base

Sleight of Flesh

Upgraded

Sleight of Flesh+

Card text

Whenever you apply a debuff to an enemy, they take 9 damage.

Sleight of Flesh+

Whenever you apply a debuff to an enemy, they take 13 damage.

Builds that use Sleight of Flesh

Archetypes that draft this card in real runs, with the role it plays.

Build context

See the Necrobinder build hub for archetypes that feature this card in real runs.

Related cards

Sleight of Flesh FAQ

Should I upgrade Sleight of Flesh in Slay the Spire 2?
Compare the upgraded text: Whenever you apply a debuff to an enemy, they take 13 damage.. If the upgrade lowers cost, adds damage/block, or enables a combo piece, it is usually high priority.
What builds use Sleight of Flesh?
Sleight of Flesh appears in 2 tracked builds: The Doom Clock (A-tier, flex pick), Rot & Ruin (B-tier, hero card).
What character uses Sleight of Flesh?
Sleight of Flesh is tagged as a Necrobinder card. See the Necrobinder build hub for archetypes that care about it.

Patch history

SpireForge snapshots card text from Untapped exports dated 2026-03-17. When Mega Crit ships a balance patch, we re-run the scraper and refresh every affected URL—see /patches for the editorial log.