Updated for Data 2026-03-17Early Access — numbers may shift with patches.

Misery

Necrobinder · Attack · Rare · 0 cost

Base

Misery

Upgraded

Misery+

Card text

Deal 7 damage. Apply any debuffs on the enemy to ALL other enemies.

Misery+

Retain. Deal 9 damage. Apply any debuffs on the enemy to ALL other enemies.

Builds that use Misery

Archetypes that draft this card in real runs, with the role it plays.

Keywords

Build context

See the Necrobinder build hub for archetypes that feature this card in real runs.

Related cards

Misery FAQ

Should I upgrade Misery in Slay the Spire 2?
Compare the upgraded text: Retain. Deal 9 damage. Apply any debuffs on the enemy to ALL other enemies.. If the upgrade lowers cost, adds damage/block, or enables a combo piece, it is usually high priority.
What builds use Misery?
Misery appears in 3 tracked builds: The Doom Clock (A-tier, flex pick), Rot & Ruin (B-tier, core card), The Gallows Doubler (B-tier, flex pick).
What character uses Misery?
Misery is tagged as a Necrobinder card. See the Necrobinder build hub for archetypes that care about it.

Patch history

SpireForge snapshots card text from Untapped exports dated 2026-03-17. When Mega Crit ships a balance patch, we re-run the scraper and refresh every affected URL—see /patches for the editorial log.