Updated for Data 2026-05-05· Untapped listing scrapeEarly Access — numbers may shift with patches.

Potion of Binding
Colorless · Uncommon
Apply 1 Weak and 1 Vulnerable to ALL enemies.
Source: Untapped.gg
Potion of Binding FAQ
- Is Potion of Binding good in Slay the Spire 2?
- Potion of Binding is a Uncommon potion: Apply 1 Weak and 1 Vulnerable to ALL enemies. It is a Colorless potion, so any character can roll or buy it. Rarer potions tend to swing harder, so weigh the immediate payoff against holding a slot open for an emergency.
- When should I use Potion of Binding?
- Drink Potion of Binding when its effect — Apply 1 Weak and 1 Vulnerable to ALL enemies. — directly answers the floor in front of you, such as an elite, boss, or a turn you would otherwise lose tempo. Holding potions for the right moment usually beats spending them on trash fights.
Related potions
- Attack Potion · Common
- Beetle Juice · Rare
- Blessing of the Forge · Uncommon
- Block Potion · Common
- Bottled Potential · Rare
- Clarity Extract · Uncommon