SpireForge

Updated for Data 2026-03-17Early Access — numbers may shift with patches.

Neutralize

Silent · Attack · Basic · 0 cost

Base

Neutralize

Upgraded

Neutralize+

Card text

Deal 3 damage. Apply 1 Weak.

Neutralize+

Deal 4 damage. Apply 2 Weak.

Keywords

Weak

Build context

See the Silent build hub for archetypes that feature this card in real runs.

Related cards

Assassinate
Backstab
Dagger Spray
Dagger Throw
Dash
Echoing Slash
Finisher
Flechettes

Neutralize FAQ

Should I upgrade Neutralize in Slay the Spire 2?
Compare the upgraded text: Deal 4 damage. Apply 2 Weak.. If the upgrade lowers cost, adds damage/block, or enables a combo piece, it is usually high priority.
What builds use Neutralize?
Neutralize is tagged as a Silent card. See the Silent build hub for archetypes that care about it.
What character uses Neutralize?
Neutralize is tagged as a Silent card. See the Silent build hub for archetypes that care about it.

Patch history

SpireForge snapshots card text from Untapped exports dated 2026-03-17. When Mega Crit ships a balance patch, we re-run the scraper and refresh every affected URL—see /patches for the editorial log.