Act 3 — Glory · Slay the Spire 2

How to beat Test Subject — Slay the Spire 2

A practical, spoiler-light breakdown of the encounter and how to play around its gimmick. Slay the Spire 2 is in Early Access, so exact HP and intent numbers shift between patches — we hedge specifics and link the wiki for live values.

Updated for Early Access patch 0.104.0

The gimmick

What Test Subject does

The one thing that defines this fight — read this before you draft your route.

A multi-phase marathon: it revives into successive phases with more HP and a fresh modifier each time, and cleanses its debuffs on transition. Reported phases punish Skill spam (gaining Strength), insert Wounds on unblocked hits, and go Intangible on alternating turns — so each phase demands a different gameplan.

Game plan

How to beat Test Subject

Ordered priorities for the fight. Tools shift by deck, but these beats hold across most archetypes.

  1. Plan for the long haul — total HP across phases is large, so conserve burst and one-time resources rather than blowing them on phase one.
  2. In the Skill-punish phase, lean on attacks and avoid spamming Skills that feed its Strength.
  3. In the Wound phase, block diligently — unblocked hits clog your deck, so prevention beats cleanup.
  4. Time your biggest hits for the turns its Intangible drops; dumping burst into an Intangible turn is wasted, since damage is shaved to 1.

By character

Class-specific tips

How each kit leans into this matchup. Open a class hub for full builds and card priorities.

Ironclad builds →

Exhaust synergies clear the Wounds it inserts, and big controlled burst lands cleanly on the non-Intangible turns.

Silent builds →

Pre-stacked poison keeps damaging it through Intangible turns and across phase transitions where direct hits stall.

Verify

Sources

Roster and mechanics cross-checked against the official wiki and EA boss coverage:

← All Slay the Spire 2 bosses